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ICBAS celebrates the ‘2nd Porto One Health Day’

Event scheduled for the International One Health Day (November 3) will bring together specialists from the most varied areas to promote the debate on this holistic approach to Health.

On the November 3rdInternational One Health Day, the Instituto de Ciências Biomédicas Abel Salazar (ICBAS) of the University of Porto will once again bring together specialists from the most varied areas and institutions in the country to promote the debate around a holistic approach to Health.

This year, with a more targeted program for the non-scientific community, the 2nd Porto One Health Day reflects the effort that the institution has been making to promote and disseminate the One Health concept among the scientific, academic and civil society communities.

For Henrique Cyrne Carvalho, director of ICBAS, this is a very important moment of affirmation of the work that ICBAS has been developing: “promoting this approach has been central to our strategy, we have held several meetings with specialists from the most varied areas, with the aim of showing that this is the way to the future and to find solutions together to promote the development and application of solutions with a view to ensuring the well-being of all, the sustainability of the planet and the promotion of public health”.

The session on November 3rd will open with the public presentation of the document 'New steps for ICBAS One Health strategy', a white paper which intends to present specific proposals for the future.

The afternoon will continue with three round tables that “are of total public interest, since they address issues that influence everyone's lives”, reinforces Henrique Cyrne Carvalho.

These topics are extremely current and include nutrition, antimicrobial resistance and health promotion in aging, in sessions that are completely open to the public “which provide an opportunity for anyone to question high-quality specialists on these topics, which we believe is fundamental. Bringing academia closer to civil society is essential to succeed in this proposal”, concludes the ICBAS director.

Starting at 2:00 p.m., in the Salão Nobre of ICBAS/FFUP, the ‘2nd Porto One Health Day’ will culminate with the opening, at 6:45 p.m., of the traveling photography exhibition “Perspective(s) on One Health”, at Aliados Metro station.

According to Cyrne Carvalho, “this is the highlight of this exhibition’s itinerancy [which represents various views on the “One Health” concept], since we can reach thousands of people a day, not only from our city, but also from various parts of the country and the world. The format will be a little different from what it has been so far, and aims to confront people with various day-to-day issues that have everything to do with this approach”.

Source: Notícias UP

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ICBAS and FFUP develop a pioneering project in the area of “Biophilia”

Project framed in the "One Health" concept aims to promote the health and well-being of those who attend the complex of the two faculties.

The ICBAS  (ICBAS) and the Faculdade de Farmácia da Universidade do Porto (FFUP) will develop a pioneering project which, based on biophilic principles and framed in the One Health, aims to promote the health and well-being of the academic community.

This is a project that goes through the incorporation of nature elements and their representations in the ICBAS/FFUP complex (indoor and outdoor spaces), with the aim of systemically influencing the health and well-being of its users.

For the director of ICBAS, Henrique Cyrne Carvalho, this project “is a way of materializing the One Health concept, but also of reinforcing our concern for the well-being of the entire community”.

“It is an ambitious project that, through biophilic design, will bring a new environment and new spaces to the ICBAS/FFUP complex, aiming at a better relationship between the community and our built space”, says Henrique Cyrne Carvalho.

Also Domingos Ferreira, director of FFUP, shares the holistic view of global health, and reinforces “the institutions’ commitment to the well-being of academic communities”. For the director of FFUP, “the project is not only ambitious, but also reinforces the position of the ICBAS/FFUP Complex as an innovative center in the promotion of health, well-being and integration with all areas of life sciences”.

What is Biophilia?

The “Biophilia Theory” argues that human beings are biologically programmed to relate to living systems and that this relationship with nature is instrumental for well-being and physical and mental health.

“With this project, we will assess the potential of biophilic design as an intervention tool in the academic space aimed at promoting health and well-being”, as Karine Silvaexplains, researcher at the Department of Behavioral Sciences at ICBAS and at ISPUP, and mentor of the scientific project.

“Based on the Theory of Biophilia, we will seek to create organic spaces in an arid landscape, which promote relaxation and psychological restoration, as well as stimulate creativity, coexistence and sharing”, he adds.

Using a participatory “photovoice”, the entire ICBAS/FFUP community will be invited to reflect on the concept of Biophilia and to contribute with suggestions for its implementation.

The collected suggestions will be subjected to a specialized and multidisciplinary analysis in the context of “focus groups”, and the resulting intervention will be evaluated regarding its impact in terms of a set of health and well-being parameters.

Karine Silva reinforces the relevance of this approach, in the post-pandemic context: “Recently, the COVID-19 pandemic strongly underlined the need to reconfigure the relationship between people and built spaces, thus reinforcing the potential of biophilic design”.

This activity is developed in partnership with the Student, Employability and Alumni Support Office. According to the coordinator of that office, Isabel Lourinho, the pandemic brought “a worsening of mental health in the university context”, which is why “it is urgent to promote mental health literacy and develop multidisciplinary activities in terms of prevention and promotion of well-being”.

This project, in addition to implementing the One Health concept, elevates the ICBAS/FFUP complex to an ambassador of biophilic design in the Portuguese academic context, promoting its recognition on the international stage as an active agent in the promotion of health and well-being.

Source: Notícias UP

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ICBAS and CIIMAR alert for the effects of lithium and microplastics consumption

The study, carried out by researchers from CIIMAR and the Instituto de Ciências Biomédicas Abel Salazar (ICBAS) of the University of Porto, was published in the journal Science of the Total Environment and identifies “for the first time” the emergence of long-term adverse effects related to the combined consumption of lithium and microplastics.

The researchers analyzed a planktonic crustacean (Daphnia magna), commonly known as the water flea, and concluded that long-term exposure to concentrations of lithium and mixtures of lithium and microplastics decreased its reproduction “up to 93% and 90% less”, respectively.

At the same time, exposure to lithium reduced the growth rate of water flea populations by 67%, and exposure to mixtures of lithium and microplastics by 58%.

The researcher Lúcia Guilhermino adds that the results are “worrying” and that the effects of the reduction in zooplankton can have “very serious consequences for ecosystems”.

“These organisms [zooplankton] represent the base of trophic chains, in addition to being essential for maintaining the quality of the water we all depend on, by filtering it while they feed,” observes the coordinator of the Laboratory of Ecotoxicology and Ecology of ICBAS.

Lúcia Guilhermino also points out that the water flea has a “very developed” nervous system, allowing the results obtained in the study to be “extrapolated” to other animals, including mammals.

The study also serves as an “alert to the effects that may be having on the human population, especially in regions rich in lithium, areas with high population density and heavy use of electronic devices, and industrial areas or areas that receive electronic waste”.

Lúcia Guilhermino, professor at ICBAS and researcher at CIIMAR, studies the biological and ecological effects of environmental contaminants and their impact on ecosystems.

“Despite its natural origin, lithium is a very reactive element from a biological point of view”, stresses Lúcia Guilhermino, noting that this element can cause “toxicity in various systems and organs, such as the nervous system, liver, kidneys and the reproductive system, through mechanisms that are not yet completely described”.

Also regarding microplastics, the researcher points out that these materials can “act like sponges and bind other contaminants, such as lithium, altering their incorporation, accumulation and toxicity”.

“All living organisms are simultaneously exposed to many pollutants throughout their lives, and the interaction between these chemical agents can lead to different toxic effects, altering the previously established safety limits”, adds Lúcia Guilhermino.

At the moment, researchers are developing studies to assess the consequences resulting from global climate change on the long-term effects of lithium, microplastics and their mixtures.

This work, which had the collaboration of the Faculty of Pharmacy of the University of Porto and CESPU — Cooperativa de Ensino Superior Politécnico e Universitário, was co-funded by the Foundation for Science and Technology (FCT), the Compete 2020 program and the North program 2020.

Source: Sapo Lifestyle

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Diet has impacts on fertility that can be inherited for two generations

Parents' food choices may have consequences on their children's health.

Um estudo desenvolvido por investigadores do Instituto de Ciências Biomédicas Abel Salazar (ICBAS), no Porto, concluiu que a alimentação produz impactos na fertilidade masculina que podem ser transmitidos e herdados por duas gerações.

O instituto revela que no estudo, publicado na revista “Molecular Nutrition & Food Research“, researchers from the Multidisciplinary Unit of Biomedical Research at ICBAS described the biomarkers that make it possible to identify a “metabolic memory” present in the testes.

The alterations are “consequences of eating a high-fat diet” and can be inherited by two generations, that is, father-son-grandson, having “implications on male fertility”. 

Marco Alves and Luís Crisóstomo, in the center of the image, at the PhD defense of ICBAS student, accompanied by the jury and the entire research team.

A equipa, liderada pelo investigador Marco Alves, já tinha determinado, em trabalhos anteriores, que a ingestão excessiva de gordura durante as primeiras fases da vida altera o conteúdo lípido e o metabolismo dos testículos, “afetando negativamente a capacidade reprodutiva durante o resto da vida” e “resultando em alterações que não são reversíveis com a mudança para uma dieta equilibrada”.

In this study, carried out in animal models (mice), the researchers “went further” and described the transgenerational effects that are transmitted by parents who eat a diet rich in fats to children and grandchildren who follow a balanced diet. 

 “The offspring showed, in the testicles, an alteration in the metabolism of choline”, an essential nutrient for the regulation of various functions, such as brain function, and the development of spermatozoa.

The investigation also showed alterations in the activity of mitochondria, in antioxidant defenses and in the presence of various lipids. 

"These alterations promote a proinflammatory environment in the testicle, altering sperm count and quality", stresses the researcher, noting that transgenerational effects are also observed when the father's intake of fat is only until puberty. 

The researcher Marco Alves points out that reproduction “is also a reflection of diet”. 

“Our food choices will have consequences for our children and, very possibly, for our grandchildren as well”, he says, adding that these effects may have even more impact on assisted reproduction processes, since the spermatozoon is chosen randomly and without taking into account biomarkers such as those identified in the study.

“The increase in infertility is clearly associated with the increase in metabolic diseases (overweight, obesity and diabetes, among others), and this association has already been recognized by the World Health Organization”, highlights Marco Alves. 

The metabolic memory in the testis is transmitted by the Sertoli cells, which respond to ensure all the structural and metabolic needs during the sperm formation process. 

The stimuli captured by these cells, in addition to altering their own genetic expression, also alter the epigenetics. 

“Knowing these changes and the transmission mechanisms will allow selecting the best spermatozoa and the best window of time to perform in vitro fertilization, improving the efficiency of assisted reproduction techniques and opening up new therapeutic opportunities in male infertility”, adds the researcher.

Além da equipa do ICBAS, o estudo contou também com investigadores da Faculdade de Farmácia da Universidade do Porto, da Universidade de Aveiro, do Instituto Politécnico da Guarda e da Associação Protetora dos Diabéticos de Portugal (APDP).

The work also resulted from several international partnerships, including the University of Zagreb and the University College of London.

Source: CNN Portugal

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OH Know More

Vaccines – a One Health super tool!

By Begoña Pérez-Cabezas, ICBAS

PORTO - Smallpox, caused by the variola virus, was one of the most devastating infectious diseases for humanity. The smallpox vaccine, created by Edward Jenner in 1796, was the first successful vaccine to be developed. Jenner observed that milkmaids who previously suffered from cowpox did not develop smallpox, and showed that a similar inoculation could be used to prevent smallpox in humans. This link between a veterinary and a human disease, established by a farmer and a physician, is an example of ther One Health approach.
Vaccines are one of the most important tools for infectious disease prevention, control and eradication. But vaccinating only people is not enough to ensure the health of all. Animal vaccines are an essential barrier to prevent the transmission of some zoonoses - diseases that spread from animals to humans. Their use can control diseases in companion and domesticated animals, such are, for instance, the Rift Valley fever and rabies. They are also useful to ensure safe food supplies through maintaining healthy livestock populations. One case in point is the vaccination of poultry against Salmonella.
But the benefits of vaccination do not stop here! Vaccines are also key for reducing antimicrobial use and to prevent the emergence and spread of drug resistance which affects the human, animal, and environmental sectors. And their use also plays a beneficial role in climate change, as the increase of animal productivity diminish the Greenhouse gas emission per kg of animal food produced.
Vaccination has a big impact on everyone's health. Be part of the solution and get vaccinated!

Image Credits: Mat Napo, Unsplash.

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Events

2nd Porto One Health Day

International One Health Day at ICBAS

3 de novembro de 2022, 14h

No próximo dia 3 de novembro, Dia Internacional Uma Saúde, o Instituto de Ciências Biomédicas Abel Salazar (ICBAS) da Universidade do Porto vai voltar a reunir especialistas das mais variadas áreas e instituições do país para promover o debate em torno de uma abordagem holística da Saúde.

Este ano, com um programa mais direcionado para a comunidade não científica, o 2nd Porto One Health Day reflete o esforço que a instituição tem vindo a fazer para promover e difundir o conceito One Health/Uma Saúde entre a comunidade científica, académica e a sociedade civil.

As comemorações terminam com a inauguração da exposição ‘Perspetiva(s) sobre Uma Saúde’, na Estação de Metro dos Aliados, às 18h45.

Inscrições here.

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Events

Photography Exhibition ‘Perspective(s) on One Health’ at CPF

This is a selection of images that portray the integrated vision of Health that ICBAS has been promoting. It is a result of the homonymous photography contest that took place in March and April 2022.

The photography contest 'Perspective(s) on One Health' promoted the dissemination of the concept among the academic community of U. Porto. About 250 images were received, from which ICBAS, together with the Portuguese Institute of Photography (IPF), a partner in this project, selected 20 photographs for a traveling exhibition which will be in several places in Porto.

The exhibition can be visited now at Centro Português de Fotografia (CPF), between October 3rd and 30th (Antiga Cadeia e Tribunal da Relação do Porto, Largo Amor da Perdição, 4050-008 Porto). Entrance is free.

This exhibition is an opportunity to promote a joint reflection on the One Health concept, as well as to alert civil society to the impact we all have on human, animal and environmental health.

See the exhibition sheet here.

Categories
Events

Photography Exhibition 'Perspective(s) on One Health' at ICBAS

This is a selection of images that portray the integrated vision of Health that ICBAS has been promoting. It is a result of the homonymous photography contest that took place in March and April 2022.

The photography contest 'Perspective(s) on One Health promoted the dissemination of the concept among the academic community of U. Porto. About 250 images were received, from which ICBAS, together with the Portuguese Institute of Photography (IPF), a partner in this project, selected 20 photographs for a traveling exhibition which will be in several places in Porto.

The exhibition can now be visited at ICBAS, located in different parts of the School, between 12 September and 4 November (R. Jorge de Viterbo Ferreira 228, 4050-313 Porto).

This exhibition is an opportunity to promote a joint reflection on the One Health concept, as well as to alert civil society to the impact we all have on human, animal and environmental health.

See the exhibition sheet here.

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Noticias

ICBAS and ISPUP launch the 'Pet-OncoNet' website for owners of pets with cancer

The aim is that owners find “credible, accurate and useful” information. There are also data about dog breeds with a greater predisposition to the development of tumors and ways to detect them early.

Professors and researchers from the Instituto de Ciências Biomédicas Abel Salazar (ICBAS) and the Instituto de Saúde Pública da Universidade do Porto (ISPUP) launched an online platform for the owners of companion animals with cancer, which aims to provide “credible” information and characterize risk factors associated with the development of the disease.

Speaking to Lusa, Kátia Pinello, Professor at ICBAS and researcher at ISPUP, clarified that the website, entitled ‘Pet-OncoNet’, arises from the logic of the ‘One Health’ concept and the need to fill a "knowledge gap in this area”.

“We feel that tutors feel lost when dealing with the diagnosis of cancer in their animal companions”, said the researcher, who is one of the project coordinators. 

Launched to provide "credible, accurate and useful" information about companion animals, the digital platform includes, for example, data on dog breeds with a greater predisposition to the development of tumors, ways to detect cancer early in pets, and also information on ongoing clinical trials and procedures to support the animal during treatment.

“Our goal is to create a community that studies and shares information about veterinary oncology in all aspects", referred.

The website shows that in Portugal, the main tumors in pets are located in the skin, followed by mammary tumors.

In addition to providing information, the platform's objective is also to characterize the risk factors associated with the development of cancer in animals and humans.

"Increasingly, animals are active members of the family. This change in attitude towards animals makes them good research models and considered 'sentinels' for cancer, since they are closer and share the same environment as humans", indicated. 

In order to make it possible to proceed with the characterization of risk factors, the researchers are inviting all tutors and owners of companion animals – cats and dogs – to respond to an epidemiological inquiry, which will be available on the website until the end of October.

The results obtained in the context of the survey will later be published on the initiative's website.

The researchers also want to create a “psychological support group” to help guardians deal with animal grief, an issue that “is not yet very well accepted”. 

“Animal grief has implications for public health”, he noted, adding that “it is important to know how to face animal grief”. 

In order to continue the project, however, the researchers need financial help, which is why it is planned to open a crowdfunding campaign on the Pet-OncoNet website.

The site, developed in partnership with Oncowaf and financed by the Belgian fund for animals with cancer, is one of the interfaces of the network Vet-OncoNet, launched in December 2019, with the aim of gathering information on neoplasms present in companion animals and creating an animal oncological registry at national level.

With the collaboration of veterinarians and diagnostic laboratories that joined the project, researchers have been able to create an animal oncology registry. The objective now is to involve owners in this network, in order to better understand the common risk factors for development of cancer in animals and humans.

Source: CNN Portugal

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Events

Photography Exhibition ‘Perspective(s) on One Health’

From June to December 2022 at various locations in Porto

On the 1st of June it opens at the Biodiversity Gallery – Centro Ciência Viva | Museum of Natural History and Science of the U. Porto, the traveling exhibition 'Perspective(s) on One Health'. This is a selection of 20 images, which portray the integrated vision of Health that ICBAS has been promoting, as a result of the homonymous photography contest that took place in March and April.

From the ‘Perspective(s) on One Health’ photo contest, which aimed to promote the dissemination of the concept among the U. Porto academic community, around 250 images were received. Of these, ICBAS, together with the Portuguese Institute of Photography (IPF), a partner in this initiative, selected 20 photographs for an itinerant exhibition that will take place in various locations in Porto:

  1. From June 2nd to July 3rd – Biodiversity Gallery
  2. July to September – ICBAS
  3. October – Portuguese Photography Center (CPF)
  4. November – Metro od Porto
  5. December – Círculo Universitário do Porto

This exhibition is an opportunity to promote a joint reflection on the One Health concept, as well as to alert civil society to the impact we all have on human, animal and environmental health.

The exhibition 'Perspective(s) on One Health' can be visited, from June 2nd to July 3rd, from Tuesday to Sunday, from 10:00 to 13:00 and from 14:00 to 18:00, at Biodiversity Gallery – Centro Ciência Viva | Museum of Natural History and Science of the U. Porto (Rua do Campo Alegre 1191, 4150-181 Porto).

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