This is a selection of images that portray the integrated vision of Health that ICBAS has been promoting. It is a result of the homonymous photography contest that took place in March and April 2022.
The photography contest 'Perspective(s) on One Health' intended to promote the dissemination of the concept in the U. Porto academic community. Around 250 images were received, of which ICBAS, together with the Portuguese Institute of Photography (IPF), a partner in this project, selected 20 for a traveling exhibition which could be visited in several places in the city of Porto.
The exhibition can now be visited, for the first time, outside Porto, at the Municipal Gallery of Alcochete City Council, between April 6 and 27, 2023 (Paços do Concelho – Largo de São João 5 – Alcochete). Free entrance.
This exhibition is an opportunity to promote a joint reflection on the One Health concept, as well as to alert civil society to the impact we all have on the health of humans, animals and the environment.
Diet has impacts on fertility that can be inherited for two generations
Parents' food choices may have consequences on their children's health.
Um estudo desenvolvido por investigadores do Instituto de Ciências Biomédicas Abel Salazar (ICBAS), no Porto, concluiu que a alimentação produz impactos na fertilidade masculina que podem ser transmitidos e herdados por duas gerações.
O instituto revela que no estudo, publicado na revista “Molecular Nutrition & Food Research“, researchers from the Multidisciplinary Unit of Biomedical Research at ICBAS described the biomarkers that make it possible to identify a “metabolic memory” present in the testes.
The alterations are “consequences of eating a high-fat diet” and can be inherited by two generations, that is, father-son-grandson, having “implications on male fertility”.
Marco Alves and Luís Crisóstomo, in the center of the image, at the PhD defense of ICBAS student, accompanied by the jury and the entire research team.
A equipa, liderada pelo investigador Marco Alves, já tinha determinado, em trabalhos anteriores, que a ingestão excessiva de gordura durante as primeiras fases da vida altera o conteúdo lípido e o metabolismo dos testículos, “afetando negativamente a capacidade reprodutiva durante o resto da vida” e “resultando em alterações que não são reversíveis com a mudança para uma dieta equilibrada”.
In this study, carried out in animal models (mice), the researchers “went further” and described the transgenerational effects that are transmitted by parents who eat a diet rich in fats to children and grandchildren who follow a balanced diet.
“The offspring showed, in the testicles, an alteration in the metabolism of choline”, an essential nutrient for the regulation of various functions, such as brain function, and the development of spermatozoa.
The investigation also showed alterations in the activity of mitochondria, in antioxidant defenses and in the presence of various lipids.
"These alterations promote a proinflammatory environment in the testicle, altering sperm count and quality", stresses the researcher, noting that transgenerational effects are also observed when the father's intake of fat is only until puberty.
The researcher Marco Alves points out that reproduction “is also a reflection of diet”.
“Our food choices will have consequences for our children and, very possibly, for our grandchildren as well”, he says, adding that these effects may have even more impact on assisted reproduction processes, since the spermatozoon is chosen randomly and without taking into account biomarkers such as those identified in the study.
“The increase in infertility is clearly associated with the increase in metabolic diseases (overweight, obesity and diabetes, among others), and this association has already been recognized by the World Health Organization”, highlights Marco Alves.
The metabolic memory in the testis is transmitted by the Sertoli cells, which respond to ensure all the structural and metabolic needs during the sperm formation process.
The stimuli captured by these cells, in addition to altering their own genetic expression, also alter the epigenetics.
“Knowing these changes and the transmission mechanisms will allow selecting the best spermatozoa and the best window of time to perform in vitro fertilization, improving the efficiency of assisted reproduction techniques and opening up new therapeutic opportunities in male infertility”, adds the researcher.
Além da equipa do ICBAS, o estudo contou também com investigadores da Faculdade de Farmácia da Universidade do Porto, da Universidade de Aveiro, do Instituto Politécnico da Guarda e da Associação Protetora dos Diabéticos de Portugal (APDP).
The work also resulted from several international partnerships, including the University of Zagreb and the University College of London.
No próximo dia 3 de novembro, Dia Internacional Uma Saúde, o Instituto de Ciências Biomédicas Abel Salazar (ICBAS) da Universidade do Porto vai voltar a reunir especialistas das mais variadas áreas e instituições do país para promover o debate em torno de uma abordagem holística da Saúde.
This is a selection of images that portray the integrated vision of Health that ICBAS has been promoting. It is a result of the homonymous photography contest that took place in March and April 2022.
The photography contest 'Perspective(s) on One Health' promoted the dissemination of the concept among the academic community of U. Porto. About 250 images were received, from which ICBAS, together with the Portuguese Institute of Photography (IPF), a partner in this project, selected 20 photographs for a traveling exhibition which will be in several places in Porto.
The exhibition can be visited now at Centro Português de Fotografia (CPF), between October 3rd and 30th (Antiga Cadeia e Tribunal da Relação do Porto, Largo Amor da Perdição, 4050-008 Porto). Entrance is free.
This exhibition is an opportunity to promote a joint reflection on the One Health concept, as well as to alert civil society to the impact we all have on human, animal and environmental health.
This is a selection of images that portray the integrated vision of Health that ICBAS has been promoting. It is a result of the homonymous photography contest that took place in March and April 2022.
The photography contest 'Perspective(s) on One Health‘promoted the dissemination of the concept among the academic community of U. Porto. About 250 images were received, from which ICBAS, together with the Portuguese Institute of Photography (IPF), a partner in this project, selected 20 photographs for a traveling exhibition which will be in several places in Porto.
The exhibition can now be visited at ICBAS, located in different parts of the School, between 12 September and 4 November (R. Jorge de Viterbo Ferreira 228, 4050-313 Porto).
This exhibition is an opportunity to promote a joint reflection on the One Health concept, as well as to alert civil society to the impact we all have on human, animal and environmental health.
From June to December 2022 at various locations in Porto
On the 1st of June it opens at the Biodiversity Gallery – Centro Ciência Viva | Museum of Natural History and Science of the U. Porto, the traveling exhibition 'Perspective(s) on One Health'. This is a selection of 20 images, which portray the integrated vision of Health that ICBAS has been promoting, as a result of the homonymous photography contest that took place in March and April.
From the ‘Perspective(s) on One Health’ photo contest, which aimed to promote the dissemination of the concept among the U. Porto academic community, around 250 images were received. Of these, ICBAS, together with the Portuguese Institute of Photography (IPF), a partner in this initiative, selected 20 photographs for an itinerant exhibition that will take place in various locations in Porto:
From June 2nd to July 3rd – Biodiversity Gallery
July to September – ICBAS
October – Portuguese Photography Center (CPF)
November – Metro od Porto
December – Círculo Universitário do Porto
This exhibition is an opportunity to promote a joint reflection on the One Health concept, as well as to alert civil society to the impact we all have on human, animal and environmental health.
The exhibition 'Perspective(s) on One Health' can be visited, from June 2nd to July 3rd, from Tuesday to Sunday, from 10:00 to 13:00 and from 14:00 to 18:00, at Biodiversity Gallery – Centro Ciência Viva | Museum of Natural History and Science of the U. Porto (Rua do Campo Alegre 1191, 4150-181 Porto).
The Department of Behavioral Sciences at ICBAS includes a research team dedicated to the production of scientific knowledge in the fields of Anthrozoology (the study of human-animal interactions) and Environmental Psychology (the study of people-environmental transactions). Special attention is given to the therapeutic potential of companion animals (dogs in particular) and to the benefits of Animal-Assisted Interventions implemented in various health and educational settings, and directed at different populations. Increasing attention is also being devoted by this research team to the health promoting effects associated with contact with natural and biophilic environments.
Clearly guided by a Health Promotion perspective, this team assumes the ultimate goal of translating scientific knowledge to society at large in order to i) support people in managing and improving their well-being through contact with animals and natural environments, ii) support the integration of animals and natural environments in health services, and iii) promote the conservation of Nature as a source of health and well-being.
In Europe, the population of companion animals has been increasing. In 2020, there were around 90 million dogs in 56 million households. In Portugal, around 38% of families had dogs as companion animals, with a total population of around 2 million animals. Thus, similarly to Europe, Portuguese households already have more pets than children, being these animals considered active elements of the family.
The growing humanization of companion animals has exacerbated the concern of tutors with food quality and safety, as well as with the impact of food on the well-being and health of animals. Indeed, tutors are increasingly looking for complete compound foods that ensure the satisfaction of nutritional needs and that, at the same time, have functional effects, especially in promoting health, well-being and longevity. Furthermore, the increase in the production of compound feed to face the increase in the animal population represents an environmental impact that cannot be neglected.
All these changes have contributed to the need to develop new food strategies, as well as to identify new ingredients that are more sustainable from an environmental, economic and social point of view and with functional qualities. The Animal Science Laboratory, at ICBAS, has developed several projects to find more sustainable food strategies that contribute to the promotion of health, well-being and longevity, both for puppies and adult dogs, towards to the societal challenge of One Health.
The research group evidences a strong and reference activity aiming the Regenerative Medicine and Tissue Engineering as critical areas of the Biomedicine and Biotechnology in a perspective of One Health. The main research projects are focused in tissue regeneration, associating innovate biomaterials to autologous/ allogenic/ xenogenic stem cells, from extra-fetal sources, like the umbilical cord blood and matrix, the bone marrow, the synovia membrane and dental pulp.
A successful demonstration is followed by the establishment of collaboration with biotechnology and pharmaceutical industries working as partners, for product development, protection of intellectual property, validation in different animal models, in a long time-scale trials and further, the future application in clinics. Excellent examples of specific programs with the Industry are: 1) Regeneration of neuromuscular tissue - an Integrative Approach; 2) Nanostructured hybrid hydrogels and synthetic bone substitutes: multifunctional injectable hydrogels for bone regeneration; 3) Development of molecular and cell-based therapies activities for Veterinary and Human Clinical Applications; 4) Pre-clinical and clinical trials of cell-based therapies and medical devices for Veterinary and Human Clinical Applications.
The multidisciplinary team, including Veterinaries, Engineers, Medical Doctors that through Experimental Surgery have a crucial role in the development of biomaterials/medical devices and cell-based therapies, allows a close share of knowledge between biomaterials design, development of cellular systems, and surgeons’ needs, with an extensive experience in advanced therapy medicinal product (ATMP) development in the bio-industry point of view, with a clear vision of what is required regulatory wise to achieve a translational final production for Animals and Humans.
Recognized scientific achievements include scientific publications, higher education and training and already 3 products in the market (cell-based therapies from dental pulp and Whärton’s jelly, and a synthetic bone substitute) and an international patent - Regenera, in the final stage of proof-of-concept for horses and companion animals.
One Health at ICBAS Aquaculture food quality and safety
Seafood is one of the food groups whose consumption is most encouraged by current nutritionists, as a result of its recognized benefits to human health. As a food of the future, in addition to sustainability, it is important to improve the methods for evaluating its quality and food safety.
The ongoing research at the Laboratory of Fish Technology of the Department of Aquatic Production of ICBAS focuses mainly on the development of new sensory, chemical and microbiological methods to assess the freshness of fish and identify its origin and authenticity. Measures to assess and improve animal welfare in aquaculture and the management and use of waste from their production are also research areas.
In sensory analysis, new tables under the 'Quality Index Method' have been created, for several aquatic species with relevance in Portugal.
In the area of chemistry, work was carried out for the nutritional and toxicological characterization (16 different elements) of species at the top of the food chain, presumably more problematic.
In microbiology, studies have been made to characterize the fish microflora, as well as the development of new microbiological techniques for characterization and identification of the origin of aquaculture species.
Waste management studies have been focused on the identification of sources, characterization of waste and its use as ingredient in feeds for animals, especially from aquaculture.
The work has also included the characterization of animal welfare in aquaculture fish, especially slaughter methods and improvement of their efficiency.
In the area of certification, a list of international systems for the certification of aquatic products and the main products was made, and technical support has been given to seafood companies in the creation of this type of systems for Portuguese products.
A balanced and healthy environment will support the growth of healthy aquatic beings, which will be adequate food items, providing health to animals and humans, confirming the modern vision of One Health we all want for our future world.
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